5-Chloro-2-methylaniline (CAS 95-79-7) is an important chemical compound used in various industrial
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5-Chloro-2-methylaniline (CAS 95-79-7) is an important chemical compound used in various industrial applications. This article provides a comprehensive overview of its properties, synthesis, applications, and safety considerations.
Property | Deskripsi |
---|---|
Rumus Molekuler | C7H8ClN |
Molecular Weight | 141.60 g/mol |
Penampilan | White crystalline solid |
Titik Melting | 52-54°C |
Boiling Point | 215°C |
Solubilitas | Slightly soluble in water, soluble in organic solvents |
5-Chloro-2-methylaniline is a white crystalline solid with a melting point of 52-54°C and a boiling point of 215°C. It is slightly soluble in water but readily dissolves in organic solvents.
Step | Process | Reagents |
---|---|---|
Starting Material | Aniline | - |
Chlorination | Electrophilic substitution | Chlorine gas or chlorinating agents |
Methylation | Nucleophilic substitution | Methyl iodide, base (e.g., NaOH) |
The synthesis of 5-Chloro-2-methylaniline typically involves the chlorination of aniline followed by methylation. Chlorination introduces the chlorine atom at the para position, while methylation adds a methyl group at the ortho position.
Aplikasi | Deskripsi | |
---|---|---|
Pharmaceuticals | Intermediate for drug synthesis | Antidepressants, antihistamines |
Dyes and Pigments | Precursor for azo dyes | Red and yellow dyes |
Agrokimia | Intermediate for pesticide synthesis | Herbicides, insecticides |
Chemical Synthesis | Building block for complex molecules | Research and industrial applications |
5-Chloro-2-methylaniline is a versatile intermediate used in the synthesis of pharmaceuticals, dyes, agrochemicals, and other complex chemical compounds. Its functional groups make it suitable for various chemical reactions.
Aspect | Deskripsi | |
---|---|---|
Toksitas | Toxic if inhaled or ingested | Causes irritation to eyes, skin, and respiratory tract |
Flammability | Flammable liquid and vapor | Keep away from heat and ignition sources |
Storage | Store in a cool, dry place | Keep in tightly closed containers |
Personal Protection | Use gloves, goggles, and proper ventilation | Avoid contact with skin and eyes |
5-Chloro-2-methylaniline is toxic and flammable. It should be handled with care, using appropriate personal protective equipment and stored in a cool, dry place away from ignition sources.
In conclusion, 5-Chloro-2-methylaniline is a valuable chemical intermediate with a wide range of applications. Its synthesis involves chlorination and methylation processes, and it is used in the production of pharmaceuticals, dyes, and agrochemicals. Proper handling and storage are essential to ensure safety in industrial and laboratory settings.
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