Name: Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylateCAS: 161798-01-2Appearance: y
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Molecular Formula: C14H13NO4S Molecular Weight: 291.32 CAS Registry Number: 161798-01-2 Density: 1.3352- (3-aldehyde 4-hydroxyphenyl) -4-methylthiazole-5-carboxylic acid ethyl ester, also known as Ugi key intermediate, has the following properties and uses:
Name: Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
CAS: 161798-01-2
Appearance: yellowish powder
Ujian: ≥99%
Kapasitas: 100mt/tahun
Min.package: 1gram
Aplikasi: Febuxostat intermediate
Standard: enterprise export
alam:
Appearance: White crystalline powder
Soluble: soluble in some organic solvents such as methanol, ethanol, and dimethylformamide
Stability: Stable, not easily decomposed
Tujuan:
Metode pembuatan:
Ethyl 2- (3-aldehyde-4-hydroxyphenyl) -4-methylthiazole-5-carboxylate can be synthesized through a multi-step reaction. A common method is to react 3-hydroxy-4-methylbenzaldehyde with ethyl methoxyacetic acid, methyl mercaptan, and dimethylformamide, and obtain the target product after acid catalysis and deprotection reaction.
Informasi keamanan:
2- (3-aldehyde 4-hydroxyphenyl) -4-methylthiazole-5-carboxylic acid ethyl ester is a chemical with certain toxicity. Please pay attention to safety when using it.
When stored, it should be sealed and kept away from sources of fire and oxidants.
When preparing and using, relevant safety operating procedures and laboratory regulations should be followed, and personal protective equipment such as laboratory gloves and protective goggles should be used.
Nama | Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate |
Sinonim | Febuxostat-23 5-karboksilato-1-etil-2-(3-forMyl-4-h Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl-5-Thiazolecarboxylate Etil 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylate Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate etil 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate ETIL 2-(3-FORMYL-4-HYDROXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE Thiazolecarboxylicacid,2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-,ethylester 2-(3-Formyl-4-hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester (2-(3-Formyl-4-hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester |
CAS | 161798-01-2 |
EINECS | 692-179-2 |
InChI | InChI=1/C14H13NO4S/c1-3-19-14(18)12-8(2)15-13(20-12)9-4-5-11(17)10(6-9)7-16/h4-7,17H,3H2,1-2H3 |
Rumus Molekuler | C14H13NO4S |
Massa Molar | 291.32 |
Kepadatan | 1.335 |
Titik Melting | 116 °C |
Titik Boling | 446.7±55.0 °C(Diperkirakan) |
Solubilitas | DMSO (Sedikit), Metanol (Sedikit) |
Penampilan | Padat |
warna | Kuning Pucat hingga Kuning |
pKa | 6.81±0.20(Diperkirakan) |
Kondisi penyimpanan | di bawah gas inert (nitrogen atau argon) pada 2-8 ° C |
Indeks Refraksi | 1.625 |
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