5-Bromo-2-methyl-4-pyrimidinecarboxylic acid

5-Bromo-2-methyl-4-pyrimidinecarboxylic acid - Names and IdentifiersName5-Bromo-2-methyl-4-pyri

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5-Bromo-2-methyl-4-pyrimidinecarboxylic acid - Names and Identifiers

Nama	5-Bromo-2-methyl-4-pyrimidinecarboxylic acid
Sinonim	2-Methyl-5-bromopyrimidine-4-carboxylicaci 5-Bromo-2-methylpyrimidin-4-carboxylic acid 5-Bromo-2-methylpyrimidine-4-carboxylic acid 5-Bromo-2-methyl-4-pyrimidinecarboxylic acid 2-methyl-5-bromopyrimidine-4-carboxylic acid 4-Pyrimidinecarboxylic acid, 5-bromo-2-methyl- 4-PyriMidinecarboxylic acid, 5-broMo-2-Methyl-
CAS	100707-39-9
InChI	InChI=1/C6H5BrN2O2/c1-3-8-2-4(7)5(9-3)6(10)11/h2H,1H3,(H,10,11)

5-Bromo-2-methyl-4-pyrimidinecarboxylic acid - Physico-chemical Properties

Rumus Molekuler	C6H5BrN2O2
Massa Molar	217.02
Kepadatan	1.795±0.06 g/cm3(Predicted)
Titik Melting	172-173 °C (decomp)(Solv: methanol (67-56-1))
Titik Boling	335.2±27.0 °C(Predicted)
Titik Flash	156.505°C
Tekanan Vapor	0mmHg di 25°C
pKa	1.53±0.10(Predicted)
Kondisi penyimpanan	Terkunci dalam kering,Suhu Kamar
Indeks Refraksi	1.61

5-Bromo-2-methyl-4-pyrimidinecarboxylic acid - Reference Information

Penggunaan

2-methyl-5-bromopyrimidin-4-carboxylic acid is a useful research chemical for organic synthesis and other chemical processes. Pyrimidine compounds are widely found in the human body and organisms. The development of such compounds has been paid attention to by the pharmaceutical and pesticide circles.

Preparation

Using 2,4-dimethyl-5-bromopyrimidine as the starting material, under alkaline conditions, potassium permanganate is oxidized to prepare the target compound 2-methyl-5-bromopyrimidin-4-carboxylic acid [1]. Or using 3, 4-dibromo-5-hydroxyfuran-2 (5h)-one as the starting material, and forming a pyrimidine ring with acetamidine hydrochloride to prepare 2-methyl-5-bromopyrimidine-4-carboxylic acid. The synthesis reaction formula of 2-methyl-5-bromopyrimidin-4-carboxylic acid is as follows: Figure 1 Synthesis reaction formula of 2-methyl-5-bromopyrimidin-4-carboxylic acid

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Sebelumnya:L-histidine dihydrochloride

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