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4,4′-Diaminodiphenylsulfone CAS 80-08-0

IntroductionCAS:80-08-0.80-08-0–NamesandIdentifiersName4-AminophenylsulfoneSynonymsDDSEPORALDap

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CAS:80-08-0.

80-08-0–NamesandIdentifiers

Name4-Aminophenylsulfone

SynonymsDDS

EPORAL

Dapsone

4.4′-DDS

DISULONE

NOVOPHONE

AVLOSULFON

SULFONA-MAE

SULPHADIONE

TIMTEC-BBSBB003168

4-Aminophenylsulfone

P-AMINOPHENYLSULFONE

4.4-Sulfonyldianiline

diaminodiphenylsulfone

P,P’-SULFONYLDIANILINE

4.4-sulphonyldianiline

4-Aminophenylsulphone

BIS(P-AMINOPHENYL)SULFONE

BIS(4-AMINOPHENYL)SULFONE

di(4-aminophenyl)sulphone

4.4′-Diaminodiphenylsulfone

4.4-Diaminodiphenylsulfone

4.4-Diaminodiphenylsulphone

4.4′-DiaminoDiphenylSulfone

4.4′-Diaminodiphenylsulphone

4.4′-DiaminoDiphenylSulphone

4-((4-aminophenyl)sulfonyl)phenylamine

4.4′-Diaminodiphenylsulfoneforsynthesis

FREESAMPLENCV4.4-DIAMINODIPHENYLSULPHONESTD

CAS80-08-0

EINECS201-248-4

InChIInChI=1/C12H10O2S.C7H6N2O5/c13-15(14.11-7-3-1-4-8-11)12-9-5-2-6-10-12;1-4-2-5(8(11)12)3-6(7(4)10)9(13)14/h1-10H;2-3.10H,1H3

InChIKeyMQJKPEGWNLWLTK-UHFFFAOYSA-N

80-08-0–Physico-chemical Properties

MolecularFormulaC12H12N2O2S

MolarMass248.3

Density1.2701(roughestimate)

MeltingPoint175-177°C(lit.)

BolingPoint511.7±35.0°C(Predicted)

WaterSolubility<0.1g/100mLat20ºC

Solubility0.38g/l

VaporPresure0.004Paat25℃

AppearanceCrystallinePowder

ColorWhitetobeige

Merck14.2822

BRN788055

pKapKb13.0(at25℃)

PH5.5-7.5(H2O,20℃)(saturatedaqueoussolution)

StorageCondition2-8°C

StabilityStable.Combustible.Incompatiblewithstrongoxidizingagents.

RefractiveIndex1.5950(estimate)

PhysicalandChemicalPropertiesMeltingpoint173-178°C

water-soluble<0.1g/100mLat20°C

UseThedrugofchoiceforthetreatmentofleprosy,canalsobecombinedwithotheranti-leprosydrugs

80-08-0–Risk and Safety

HazardSymbolsXn–Harmful

RiskCodes22–Harmfulifswallowed

SafetyDescription22–Donotbreathedust.

UNIDs3249

WGKGermany1

RTECSBY8925000

TSCAYes

HSCode29309070

HazardClass6.1(b)

PackingGroupIII

ToxicityLD50orallyinRabbit:1000mg/kgLD50dermalRabbit>4000mg/kg

80-08-0–Standard

This product is 4.4‘-sulfonylbis-aniline.Calculated as the dried product,the content of C12H12N202S shall no tbe less than 99.0%.

80-08-0–Trait

This product is white or off-white crystalline or crystalline powder;Odorless.

This product is soluble in acetone,dissolved in methanol,slightly soluble in ethanol,almost insoluble in water;Dissolved in dilute hydrochloric acid.

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