N-acetyl-3-5-diiodo-L-tyrosine - Names and IdentifiersNameN-acetyl-3-5-diiodo-L-tyrosineSynonym
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Nama | N-acetyl-3-5-diiodo-L-tyrosine |
Sinonim | AC-3,5-DIIODO-TYR-OH N-Acetyl-3,5-diiodotyrosine N-Acetyl-3,5-diiodo-L-tyrosine N-ACETYL-3,5-DIIODO-L-TYROSINE N-acetyl-3-5-diiodo-L-tyrosine 3,5-Diiodo-N-Acetyl-L-Tyrodine 3,5-DIIODO-N-ACETYL-L-TYROSINE N-Acetyl-3,5-Diiodo-L-tyrosine dihydrate 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid 2-(Acetylamino)-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid (2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid Levothyroxine Related Compound (N-Acetyl-3,5-Diiodo-L-Tyrosine) |
CAS | 1027-28-7 |
EINECS | 213-837-3 |
InChI | InChI=1/C11H11I2NO4/c1-5(15)14-9(11(17)18)4-6-2-7(12)10(16)8(13)3-6/h2-3,9,16H,4H2,1H3,(H,14,15)(H,17,18)/t9-/m0/s1 |
Rumus Molekuler | C11H11I2NO4 |
Massa Molar | 475.02 |
Kepadatan | 2.206±0.06 g/cm3(Predicted) |
Titik Melting | 124.0 to 128.0 °C |
Titik Boling | 532.9±50.0 °C(Predicted) |
Titik Flash | 276.1°C |
Solubilitas | almost transparency in Methanol |
Tekanan Vapor | 3.47E-12mmHg at 25°C |
Penampilan | Kristalisasi |
warna | Putih hingga kuning cahaya hingga oranye cahaya |
pKa | 2.98±0.10(Predicted) |
Kondisi penyimpanan | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
Indeks Refraksi | 1.692 |
MDL | MFCD00020004 |
Sifat fisik dan kimia | Property description: white crystalline compound, melting point 178-182 ℃ |
Penggunaan | Iodothyronin (triiodothyronine) intermediate, pharmaceutical raw material. |
Deskripsi Keselamatan | Please take the official translations! You find them here: http: // europa. eu. int/ eur- lex/ lex/ LexUriServ/ LexUriServ. do? uri=CELEX: 32001L0059: EN: HTML S24/25 Hindari kontak dengan kulit dan mata. |
WGK Jerman | 3 |
Penggunaan | N-acetyl -3, 5-diiodo-L-tyrosine has been used in the simulation system of thyroid hormone biosynthesis. In addition, the ability of N-acetyl -3, 5-diiodo-L-tyrosine to inhibit pepsin-catalyzed hydrolysis was also studied to determine the substrate binding region of the enzyme activity center. Triiodothyronine intermediate. |
metode produksi | tyrosine is first iodized with iodine and hydrochloric acid to generate 3,5-diiodotyrosine, and then acylated with acetic anhydride to obtain the product. |
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