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Vitamin E Acetate (D-α-Tocopheryl acetate), with CAS number 7695-91-2. is a stabilized ester form of vitamin E widely used in cosmetics, pharmaceuticals, and food industries. This article examines its chemical properties, industrial applications, and safety profile.
| Property | Specification |
|---|---|
| Rumus Molekuler | C₃₁H₅₂O₃ |
| Molecular Weight | 472.75 g/mol |
| Penampilan | Pale yellow viscous oil |
| Titik Melting | 25-28°C |
| Boiling Point | 224°C (0.1 mmHg) |
| Solubilitas | Insoluble in water; soluble in oils and organic solvents |
| Stabilitas | Oxidatively stable; hydrolyzes in strong acids/alkalis |
The acetate form provides enhanced stability compared to free tocopherol, with longer shelf life and better heat resistance.
| Application Sector | Purpose | Typical Concentration Range |
|---|---|---|
| Cosmetic Products | Antioxidant, skin conditioner | 0.5-5% |
| Pharmaceutical | Vitamin E supplement | 100-400 IU per dose |
| Food Additive | Nutritional fortification | 0.01-0.1% of fat content |
| Animal Feed | Growth promoter | 50-300 mg/kg feed |
In skincare formulations, it protects against UV-induced damage while maintaining product stability.
Table 3: Safety and Regulatory Status
| Parameter | Assessment |
|---|---|
| Oral Toxicity (LD50) | >10.000 mg/kg (rat) |
| Skin Irritation | Non-irritating (rabbit tests) |
| Eye Irritation | Mild irritant |
| Regulatory Status | GRAS (FDA); Approved in EU CosIng |
| Recommended Daily Intake | 15 mg (adults) |
The global market for vitamin E acetate is projected to grow at 6.2% CAGR through 2028. driven by increasing demand from anti-aging cosmetics and nutraceutical sectors.
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